"Over 120M patients suffer from osteoarthritis (OA) worldwide. There is no cure. Theragen is focused on finding the cure"

What is osteoarthritis?

Osteoarthritis (OA) is a degenerative disease of the joints. OA impacts both matrix and articular cartilage layers of affected joints. High resolution medical imaging demonstrates diminishing thicknesses of joint cartilage as OA progresses. In advanced cases of OA, cartilage can be destroyed until the subchondral bone (bone which was once covered by cartilage) is exposed, and the joint essentially has no cartilage between opposing bones in the joint. The degenerative process of osteoarthritis progression can cause pain and immobility in patients during early and late phases. Scientists and physicians have identified a number of underlying processes that trigger and drive continuing OA damage to joints. The Arthritis Foundation states that more than 27 million patients suffer from OA in the US. Estimates exceed 120M+ patients worldwide suffering from degenerative OA. Most commonly, patients seek treatment for OA disease of the knees, hips, shoulders, elbows, and hands & feet. There is no cure. However, there are treatments which include exercise, physical therapy and pain medications used to avoid surgical intervention. For many patients, OA inevitably leads to joint replacement for the relief of intractable pain and the restoration of mobility.”

Theragen’s non-invasive electrical technology is being developed to positively influence biochemical and gene expression pathways to promote cartilage regeneration, and to reduce negative processes contributing to cartilage erosion.



Arthritis Foundation


Arthritis Research Foundation


American College of Rheumatology


Arthritis National Research


The Osteoarthritis Research Society


Hospital for Joint Diseases